The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 2004

Filed:

Aug. 22, 2000
Applicant:
Inventors:

M. Bud Nelson, Worthington, OH (US);

Emilio Barbera-Guillem, Powell, OH (US);

Assignee:

BioCrystal, Ltd., Westerville, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 3/3543 ; G01N 3/3564 ;
U.S. Cl.
CPC ...
G01N 3/3543 ; G01N 3/3564 ;
Abstract

Provided are methods, and assay kits, and compositions useful for generating an indicator of a disease condition selected from the group consisting of multiple sclerosis (MS), a pro-MS immune response, and a combination thereof. A method for assaying a sample of an individual for an indicator of the disease condition comprises contacting the sample with a combination of two or more affinity ligands, at least one of which comprises a detection reagent; measuring an amount of the detection reagent which is bound to the sample in determining a value of a marker in the sample; wherein a difference in the value of the marker determined in the sample, when compared to the reference value, comprises an indicator of the presence of the disease condition.


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