The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 06, 2004

Filed:

Apr. 29, 2002
Applicant:
Inventors:

Nathan A. Thomas, Louisville, KY (US);

John C. Vellinger, Floyd Knobs, IN (US);

Paul W. Todd, Greenville, IN (US);

Shramik Sengupta, Minneapolis, MN (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01D 5/702 ; C02F 1/469 ; G01N 2/726 ; G01L 1/20 ; C25B 1/500 ;
U.S. Cl.
CPC ...
B01D 5/702 ; C02F 1/469 ; G01N 2/726 ; G01L 1/20 ; C25B 1/500 ;
Abstract

An electrophoresis device is disclosed which separates cells, particles, proteins and other separands by collecting samples of decreasing electrophoretic mobility in a train of inverted cavities while an electric field is applied between said inverted cavities and one or more sample cuvettes containing a mixture of cells, particles, proteins or other separands. One circular plate is provided for the one or more sample cuvettes, and one circular plate is provided for the multiple collection cavities. The invention utilizes an innovative purification method that combines free electrophoresis and multistage extraction in an instrument capable of separating living cells, particles, and proteins in useful quantities at high concentrations. The purification method includes a method for dealing with electrolysis products, a technique for controlling the electrical energy input, and an approach for keeping the process isothermal. The invention solves many separation applications problems on earth and also in reduced gravity in space flight.


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