The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 22, 2004

Filed:

Apr. 19, 2002
Applicant:
Inventors:

Ly Tam Phan, Malden, MA (US);

Yao-Ling Qiu, Somerville, MA (US);

Yat Sun Or, Cambridge, MA (US);

Nha Vo, Malden, MA (US);

Tianying Jian, Boston, MA (US);

Ying Hou, Everett, MA (US);

Marina Busuyek, Natick, MA (US);

Assignee:

Enanta Pharmaceuticals, Inc., Watertown, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/17048 ; C07H 1/708 ;
U.S. Cl.
CPC ...
A61K 3/17048 ; C07H 1/708 ;
Abstract

There are described novel 5-O-mycaminosyltylonide (OMT) analogs possessing increased antibacterial activity toward Gram positive and Gram negative bacteria as well as macrolide resistant Gram positives and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described are a method for treating bacterial infections by administering to a patient a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention, and processes for the preparation of such compounds


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