The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 2004
Filed:
Jul. 03, 2001
William R. Jacobs, Jr., City Island, NY (US);
Barry Bloom, Hastings-on-Hudson, NY (US);
Ganjam V. Kalpana, Yonkers, NY (US);
Jeffrey D. Cirillo, Mountain View, CA (US);
Ruth McAdam, Near Hatfield, GB;
Albert Einstein College of Medicine of Yeshiva University, Bronx, NY (US);
Abstract
A mutated mycobacterium selected from the class consisting of mutated -BCG, mutated and mutated . The mutation of -BCG, or is preferably effected through an insertional mutation of a mycobacterial gene. The insertional mutagenesis may be effected, for example, through illegitimate recombination or by a mycobacterial transposon. Such mutated mycobacteria may then be transformed with an expression vector(s) containing a complement gene to the gene which is mutated, and preferably also including a heterologous gene.