The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 15, 2004

Filed:

Apr. 26, 2002
Applicant:
Inventors:

Robert Edward Morris, Eire, IE;

Peter John Sadler, Penicuik, GB;

Haimei Chen, Edinburgh, GB;

Duncan Jodrell, Edinburgh, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 1/702 ; A61K 3/1555 ; A61K 3/1295 ; A61P 3/500 ;
U.S. Cl.
CPC ...
C07F 1/702 ; A61K 3/1555 ; A61K 3/1295 ; A61P 3/500 ;
Abstract

Compounds which may be used in the treatment and/or prevention of cancer have the formula (I) wherein: R , R , R , R , R and R independently represents H, alkyl, —CO R′, aryl or akylaryl, which latter two groups are optionally substituted on the aromatic ring; R′ represent alkyl, aryl or alkaryl; X is halo, H O, (R′)(R″)SO, R′CO — or (R′)(R″)C═O, where R″ represents alkyl, aryl or alkaryl; Y is a counterion; m is 0 or 1; q is 1, 2 or 3; C′ is C to C alkylene, optionally substituted in or on the alkylene chain, bound to two A groups; p is 0 or 1 and r is 1 when p is 0 and r is 2 when p is 1; and A and B are: each independently N-donor nitrile ligands; or B is halo and A is an N-donor pyridine ligand, optionally substituted at one or more of the carbon atoms of the pyridine ring; or p is 0, A is NR R and B is NR R , wherein R , R , R and R independently represent H or alkyl, and A and B are linked by an alkylene chain, optionally substituted in or on the alkylene chain, or p is 1, A is NR and B is NR R , wherein R , R and R are as previously defined, and A and B are linked by an alkylene chain, optionally substituted.


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