The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2004
Filed:
Feb. 03, 2003
Applicant:
Inventors:
Alfred H. Merrill, Jr., Dunwoody, GA (US);
Lisa Warden, Stroudsburg, PA (US);
Dennis C. Liotta, Atlanta, GA (US);
Assignee:
Emory University, Atlanta, GA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/133 ; A61K 3/1434 ; A61K 3/144 ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/133 ; A61K 3/1434 ; A61K 3/144 ; C07D / ; C07D / ;
Abstract
Compositions, methods of use, isolation and biosynthesis of diimino-piperazine derivatives useful for the modification of sphingolipid metabolism and other biological functions are described. The preferred derivative is 2,6-bis-(&ohgr;-aminobutyl)-3,5-diimino-piperazine. This is a naturally occurring biochemical compound isolated from cells. The diimino-piperazine derivatives are useful as therapeutic agents when administered to patients to treat diseases and disorders involving cell regulation.