The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 15, 2004

Filed:

Nov. 15, 2000
Applicant:
Inventors:

Cindra A. Widrig Opalsky, Ottawa, CA;

David Opalsky, Ottawa, CA;

Andy Maczuszenko, Toronto, CA;

Imants R. Lauks, Rockcliffe Park, CA;

Rhonda J. Cheadle, Ottawa, CA;

Assignee:

i-STAT Corporation, East Windsor, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/34 ;
U.S. Cl.
CPC ...
C12M 1/34 ;
Abstract

This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate.


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