The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 2004
Filed:
Aug. 15, 2000
Applicant:
Inventors:
Mahendra G. Dedhiya, Dublin, OH (US);
Julia J. Economou, HIlliard, OH (US);
Andrea M. McPhillips, Columbus, OH (US);
Beverley A. Wynne, Worthington, OH (US);
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 4/316 ; A01N 2/502 ; A61K 3/135 ; A61K 4/00 ; A61L 9/04 ;
U.S. Cl.
CPC ...
A01N 4/316 ; A01N 2/502 ; A61K 3/135 ; A61K 4/00 ; A61L 9/04 ;
Abstract
A formulation of delta-9-tetrahydrocannabinol in a semi-aqueous solvent, such as 35:10:55 alcohol:water:propylene glycol (v/v), produces a stable clear solution near the solubility point of the drug. Because delta-9-tetrahydrocannabinol has poor affinity for the formulation, it is able to partition out and transport across cell membranes to reach the bloodstream quickly. This has been demonstrated by the comparative t values achieved in single dose intravenous and 14 day multiple dose inhalation studies conducted in dogs and rats.