The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2004
Filed:
Mar. 11, 2002
Hiroko Isoda, Tsukuba, JP;
Takashi Koyama, Yuki, JP;
Masako Tasaki, Tsukuba, JP;
Syuichi Oka, Tsukuba, JP;
Norio Sugiura, Tsuchiura, JP;
Takaaki Maekawa, Ibaraki, JP;
Yuhei Inamori, Tsukuba, JP;
Shinichi Yokota, Takasago, JP;
Mikio Kitahara, Kobe, JP;
Kazuhiro Nagata, Kyoto, JP;
Other;
Abstract
The present invention provides a bioassay system, for detection of hazardous chemical substances, natural toxic substances in the environment and unknown toxic compounds, with high sensitivity, simplicity and speed. The invention provides cells and a method of using the cells for use in the bioassay system. The cell provided by the invention contains a heat shock factor binding DNA sequence and a transcriptional regulatory sequence necessary on an occasion of stress induction as a transcriptional regulatory factor binding site. The cell also possesses a reporter gene under the control of the promoter. The reporter gene is connected, on the downstream side, to the SV40pA signal without any intervening intron.