The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6737550 B1

PDF
Full Text
Expired
Date of Patent:
May. 18, 2004

Filed:

Jun. 13, 2002
Applicant:
Inventors:

Ben-Zion Dolitzky, Petach Tikva, IL;

Ofer Reany, Lower Gallilee, IL;

Jenny Shammai, Kiryat Yam, IL;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; C07C / ;
U.S. Cl.
CPC ...
C07C / ; C07C / ;
Abstract

The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{4-fluorophenyl sulfone}]-2-hydroxy propionate, 1,2-epoxy-2-methyl propionate and 2-hydrox-2-methyl-3-(4-fluorophenylthio) propionic acid. The present invention further discloses micronized rac-bicalutamide and the preparation thereof.


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Dolitzky, Ben-Zion. (2004). Process for preparing rac-bicalutamide and its intermediates (U.S. Patent No. 6737550). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6737550

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