The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 18, 2004
Filed:
Aug. 03, 2000
Rima L. McLeod, Chicago, IL (US);
Craig W. Roberts, Glasgow, GB;
Fiona Roberts, Glasgow, GB;
Jennifer J. Johnson, Stillwater, MN (US);
Michael Kirisits, Chicago, IL (US);
David Ferguson, Tackley Oxford, GB;
Russell Lyons, Glasgow, GB;
Ernest Mui, Chicago, IL (US);
Doug Mack, Riverside, IL (US);
Benjamin Samuel, Chicago, IL (US);
Piotr Gornicki, Chicago, IL (US);
Ellen Zuther, Beuhy, DE;
Apicomplexan Therapeutics, LLC, Oak Lawn, IL (US);
Abstract
This invention relates uses of chorismate synthase, a component components of plant-like metabolic pathways not including psbA or PPi phosphofructokinase and not generally operative in animals or encoded by the plastid DNA, in assays to develop compositions that interfere with Apicomplexan growth and survival. Components of the pathways include enzymes, transit peptides and nucleotide sequences encoding the enzymes and peptides, or promoters of these nucleotide sequences to which antibodies, antisense molecules and other inhibitors are directed. Diagnostic and therapeutic reagents and vaccines are developed based on chorismate synthase and its inhibitors.