The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2004
Filed:
Jun. 13, 2002
Applicant:
Inventors:
David J. Grainger, Cambridge, GB;
James C. Metcalfe, Cambridge, GB;
Sudhakar Kasina, Mercer Island, WA (US);
Assignee:
NeoRx Corporation, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/138 ;
U.S. Cl.
CPC ...
A61K 3/138 ;
Abstract
The invention provides a method of treating a mammal having, or at risk of, an indication associated with a TGF-beta deficiency comprising administering one or more agents that is effective to elevate the level of TGF-beta. The invention also provides novel compounds that elevate TGF-beta levels, as well as pharmaceutical compositions comprising compounds that elevate TGF-beta levels, and methods for detecting diseases associated with endothelial cell activation.