The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6734207 B1

PDF
Full Text
Expired
Date of Patent:
May. 11, 2004

Filed:

Apr. 18, 2002
Applicant:
Inventors:

Fatih M. Uckun, White Bear Lake, MN (US);

Shyi-Tai M. Jan, Roseville, MN (US);

Assignee:

Parker Hughes Institute, Roseville, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/138 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/138 ; C07D / ;
Abstract

Compounds are described that bind to tubulin causing tubulin depolymerization and inhibiting tubulin polymerization. The compounds of the invention are therapeutically effective to inhibit cellular proliferation, for example, as effective anti-cancer agents. The compounds can also induce cytotoxicity in cells such as leukemia cells. The chemical structure of the compounds includes a furan, thiophene, thiazole, oxazole, or imidazole group at one end of the molecule (head) and a hydrophobic, aliphatic chain at the other end of the molecule (tail).


Find Patent Forward Citations

Uckun, Fatih. (2004). Cytotoxic compounds (U.S. Patent No. 6734207). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6734207

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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