The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2004
Filed:
Mar. 07, 2002
Michael D. Lackhart, Charlottesville, VA (US);
Veridan Systems Division, Ann Arbor, MI (US);
Abstract
Coupled fiber-optic, evanescent-wave biosensors are improved through the use of configurations which detect changes in polarization for enhanced sensitivity. The inventive approach forms the necked-down region by heating and pulling the fibers without twisting them. As such, when polarized light is introduced, including randomly polarized light, the outputs will exhibit a split based upon polarization orientation as well. One or more bindings partners are then attached to the necked-down region and within the evanescent field for very specific and direct detection of minute concentrations of an analyte of interest. The invention is applicable to any type of organic/inorganic material, so long as the interaction of one component causes a change in any optical property detectable by the apparatus. The biomolecule may be linked to the surface of the fusion joint by means of a spacer molecule. Polarizing beam splitters are employed to detect the based upon polarization orientation.