The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 04, 2004

Filed:

Dec. 13, 2002
Applicant:
Inventors:

Britta Evers, Hamburg, DE;

Cynthia Darshini Jesudason, Indianapolis, IN (US);

Rushad Eruch Karanjawala, Zionsville, IN (US);

David Michael Remick, Fishers, IN (US);

Daniel Jon Sall, Greenwood, IN (US);

Miles Goodman Siegel, Indianapolis, IN (US);

Wolfgang Stenzel, Reinbek, DE;

Russell Dean Stucky, Indianapolis, IN (US);

John Arnold Werner, Greenwood, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; A61K 3/144 ; C07C / ;
U.S. Cl.
CPC ...
C07D / ; A61K 3/144 ; C07C / ;
Abstract

The present invention relates to a &bgr; adrenergic receptor agonist of formula (I) or a pharmaceutical salt thereof, which is capable of increasing lipolysis and energy expenditure in cells and, therefore, is useful for treating Type II diabetes and/or obesity. The compound can also be used to lower triglyceride levels and cholesterol levels or raise high density lipoprotein levels or to decrease gut motility. In addition, the compound can be used to reduced neurogenic inflammation or as an antidepressant agent. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for decreasing gut motility are also disclosed.


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