The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 04, 2004
Filed:
Apr. 12, 2001
Applicant:
Inventors:
Michael W. Riggs, Tucson, AZ (US);
Lance E. Perryman, Cary, NC (US);
Assignee:
Other;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/9012 ; A61K 3/520 ; A61K 3/9395 ; C07K 1/444 ; C12N 5/20 ;
U.S. Cl.
CPC ...
A61K 3/9012 ; A61K 3/520 ; A61K 3/9395 ; C07K 1/444 ; C12N 5/20 ;
Abstract
Compositions and methods useful for conferring passive or active immunity to the parasite, . A high molecular weight glycoprotein antigen isolated from , capable of binding the mAb 3E2, was shown to harbor an epitope critical for triggering the neutralizing CSP-like reaction in the parasite. Antibodies targeted against the critical epitope were shown to possess neutralizing activity, and could be combined with other anti- monoclonal antibodies and administered to an animal to confer passive immunity. Immunogenic compositions including the purified antigen are disclosed for use in stimulating an active immune response against