The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 27, 2004

Filed:

Jul. 01, 2002
Applicant:
Inventors:

Nagesh Palepu, Mill Creek, WA (US);

Dean Kessler, Edmonds, WA (US);

Alexander K. Tustian, Mukilteo, WA (US);

Steven C. Quay, Edmonds, WA (US);

Panayiotis P. Constantinides, Gurnee, IL (US);

Karel J. Lambert, Seattle, WA (US);

Assignee:

Sonus Pharmaceuticals, Inc., Bothell, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/121 ; A61K 3/1355 ; A61K 9/14 ; A61K 9/65 ; A01N 2/500 ;
U.S. Cl.
CPC ...
A61K 3/121 ; A61K 3/1355 ; A61K 9/14 ; A61K 9/65 ; A01N 2/500 ;
Abstract

The present invention provides methods for administering a taxane composition for the treatment of cancer. In one aspect, the compositions are not diluted prior to administration. Some embodiments provide methods for administering a taxane as a bolus injection or an intravenous infusion in less than about 30 minutes. In other aspects, the invention provides methods for administering a taxane to provide high concentrations of the taxane in blood or in tumors. Another aspect provides methods for administering a taxane to provide anti-tumor activities against solid tumors. In some embodiments, the methods provide anti-tumor activities against tumors that were resistant to conventional taxane administration methods. In some embodiments, the methods provide anti-tumor activities against colorectal tumors.


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