The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 2004

Filed:

Dec. 18, 2000
Applicant:
Inventors:

Sylvie Laquerre, Danville, CA (US);

Terry Hermiston, Corte Madera, CA (US);

Assignee:

Onyx Pharmaceuticals, Inc., Richmond, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/576 ; A01N 6/300 ; C12N 7/01 ;
U.S. Cl.
CPC ...
A61K 3/576 ; A01N 6/300 ; C12N 7/01 ;
Abstract

The present invention relates to pharmaceutical compositions, kits, and methods of use thereof, comprising, a mutant human herpes simplex virus, which is cytopathic to susceptible target cells, such as neoplastic cells. Preferably, the virus does not produce a functionally active wild-type gC polypeptide coded for the UL44 gene.


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