The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2004
Filed:
Jul. 17, 1997
Applicant:
Inventors:
Stefan Janssens, Heverlee, BE;
Kenneth D. Bloch, Brookline, MA (US);
Désiré Collen, Winksele, BE;
Assignee:
Other;
Primary Examiner:
Int. Cl.
CPC ...
A61K 4/800 ; C12N 1/500 ; C12N 1/563 ; C12N 1/587 ;
U.S. Cl.
CPC ...
A61K 4/800 ; C12N 1/500 ; C12N 1/563 ; C12N 1/587 ;
Abstract
This invention relates to a gene therapy method for inducing pulmonary vasodilation. More specifically, this invention involves introducing the nitric oxide synthase gene into lungs resulting in pulmonary vasodilation. This results in a hypotensive effect in the pulmonary circulation which does not significantly affect systemic blood pressure or cardiac index. This method is useful to treat primary pulmonary hypertension or pulmonary hypertension secondary to various disease states.