The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2004
Filed:
Nov. 27, 2001
Use of antimicrobial proteins and peptides for the treatment of otitis media and paranasal sinusitis
David J. Lim, Pasadena, CA (US);
Haa-Yung Lee, La Crescenta, CA (US);
Paul Webster, Pasadena, CA (US);
Ali Andalibi, Studio City, CA (US);
Jian-Dong Li, Glendale, CA (US);
Tomas Ganz, Los Angeles, CA (US);
House Ear Institute, Los Angeles, CA (US);
Abstract
Disclosed herein is a method for the treatment of otitis media and paranasal sinusitis using human defensins, lysozyme and/or lactoferrin as a new class of non-antibiotic antimicrobials. From studies of otitis media and paranasal sinusitis, it was observed that certain innate immune modulators were important in the bodies response to the infection. Therefore, these innate immune modulators, lysozyme, lactoferrin and defensins, were tested for use as a non-antibiotic treatment for infection, particularly infections such as otitis media and sinusitis.