The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 06, 2004

Filed:

Jul. 20, 2000
Applicant:
Inventors:

Steven E. Cwirla, Menlo Park, CA (US);

Palani Balu, Cupertino, CA (US);

David J. Duffin, Durham, NC (US);

Sunila Piplani, Mountain View, CA (US);

Barbara McEowen Merrill, Durham, NC (US);

Peter J. Schatz, Cupertino, CA (US);

Assignee:

Affymax, Inc., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 4/304 ; A61K 3/800 ; C07K 1/700 ;
U.S. Cl.
CPC ...
A01N 4/304 ; A61K 3/800 ; C07K 1/700 ;
Abstract

Novel compounds are provided that bind to G-CSFR. The novel compounds have a peptide chain approximately 6 to 40 amino acids in length that binds to G-CSFR. The compounds are useful as probes for affinity screening. In addition, the compounds have demonstrated agonist or antagonist activity for the G-CSFR, and are therefore useful in treatment of diseases including patients who suffer from a low white blood cell titer. Pharmaceutical compositions and methods of use are provided as well.


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