The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2004
Filed:
Jan. 25, 1995
Applicant:
Inventors:
James Cleland Paton, Parkside, S.A. 5063, AU;
David John Hansman, Rose Park, S.A. 5067, AU;
Graham John Boulnois, Cheshire, SK9 7QJ, GB;
Peter William Andrew, Leistershire LE1 9HN, GB;
Timothy John Mitchell, Appleby Magna, Burton-on-Trent Straffordshire DE12 7AA, GB;
John Arthur Walker, Memphis, TN (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/900 ; A61K 3/938 ; A61K 3/902 ; A61K 3/909 ;
U.S. Cl.
CPC ...
A61K 3/900 ; A61K 3/938 ; A61K 3/902 ; A61K 3/909 ;
Abstract
Mutants of pneumolysin that are non-toxic by reason of amino acid substitutions have been constructed. These mutants elicit an immune response in animals that is reactive to wild-type pneumolysin. The invention also encompasses vaccines for humans based on these mutants, including vaccines comprising conjugates with pneumococcal capsular polysaccharides.