The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 30, 2004

Filed:

Jan. 18, 2002
Applicant:
Inventors:

Kazuo Nishimura, Osaka, JP;

Masakazu Ban, Osaka, JP;

Ken-ichi Fujimura, Osaka, JP;

Naoyuki Kobayashi, Osaka, JP;

Masanori Hori, Osaka, JP;

Eiko Matsumoto, Ashiya, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; A61K 3/1496 ; A61P 9/04 ;
U.S. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; A61K 3/1496 ; A61P 9/04 ;
Abstract

A compound which is a chymase inhibitor and which is represented by a formula [I] and salts thereof. In the formula [I], X is R —(A ) —N, R and R are H, alkyl, cycloalkyl or aryl, R and R are H, alkyl, cycloalkyl, aryl or aromatic heterocycle, R is H, alkyl, cycloalkyl, aryl or —A —A —R , R is H, alkyl, cycloalkyl, OH, alkoxy, aryl, aryloxy or an aromatic heterocycle, R is H, alkyl, OH, alkoxy, aryl, aryloxy, amino, alkylamino, arylamino, an aromatic heterocycle or a nonaromatic heterocycle, A is alkylene, A is carbonyl or sulfonyl, A is alkylene, A is carbonyl or oxalyl and n is o or 1. The formula [I] is


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