The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 23, 2004
Filed:
Aug. 08, 2002
Elizabeth Janet Pease, Macclesfield, GB;
Gloria Anne Breault, Macclesfield, GB;
Robert Hugh Bradbury, Macclesfield, GB;
AstraZeneca, Sodertalje, SE;
Abstract
Pyrimidine derivatives of the formula (I) wherein: one of Q and Q or both of Q and Q is substituted on a ring carbon by one substituent of the formula (Ia) [provided that when present in Q the substituent of formula (Ia) is not adjacent to the —NH— link]; wherein Q , Q , G, R , X, Y , Y , Z, n and m are as described within; and pharmaceutically acceptable salts and in vivo hydrolyzable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described.