The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2004
Filed:
Jun. 26, 2000
Applicant:
Inventors:
William Robert Carling, Bishops Stortford, GB;
Andrew Mitchinson, Sawbridgeworth, GB;
Leslie Joseph Street, Little Hallingbury, GB;
Assignee:
Merck Sharp & Dohme Ltd., Hoddesdon, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 2/508 ; A60K 3/15025 ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61P 2/508 ; A60K 3/15025 ; C07D / ; C07D / ; C07D / ;
Abstract
1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing an optionally substituted cycloalkyl, phenyl or heteroaryl substituent at the 3-position, a substituted alkoxy moiety at the 6-position, an optionally substituted N-linked nitrogen-containing aliphatic ring at the 7-position, and a chloro at the 8-position are selective ligands for GABAZ receptors, in particular having high affinity for the &agr;2 and/or &agr;3 subunit thereof, are useful in the treatment of anxiety and convulsions.