The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2004
Filed:
Nov. 06, 2001
John C. Vellinger, Floyd Knobs, IN (US);
Paul W. Todd, Greenville, IN (US);
Kenneth W. Barton, Greenville, IN (US);
Scott Dunn, Pendleton, KY (US);
Mark S. Deuser, Floyd Knobs, IN (US);
Space Hardware Optimization Technology, Inc., Greenville, IN (US);
Abstract
The present invention relates to improved techniques for separating cells, particles and molecules important to medical science and biotechnology because separation is frequently the limiting factor for many biological processes. The apparatus and method of use provides an innovative method for quantitatively separating cells, proteins, or other particles, using multistage, magnetically, electromagnetically assisted separation technology, (“MAGSEP”). The MAGSEP technology provides a separation technology applicable to medical, chemical, cell biology, and biotechnology processes. Moreover, the instant invention relates to a method for separating and isolating mixtures of combinatorial synthesized molecules such that a variety of products are prepared, in groups, possessing diversity in size, length, (molecular weight), and structural elements. These are then analyzed for the ability to bind specifically to an antibody, receptor, or other ligate. Such a collection may provide a ligand library containing specific ligands for any ligate even though there are a greater number of conformations available to any one sequence. This technology provides a cell biologists a tool for studying molecular recognition. Combinational chemical libraries containing known and random sequences can be surveyed for strong ligands. Such a tool provides a means of recognizing and isolating agonists, antagonists, enzyme inhibitors, virus blockers, antigens, and other pharmaceuticals, but more significantly quantities of receptors on biological cells in aqueous suspensions including body fluids.