The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2004
Filed:
Apr. 05, 2001
Amir Snapir, Turku, FI;
Paula Heinonen, Turku, FI;
Pia Alhopuro, Turku, FI;
Matti Karvonen, Turku, FI;
Markku Koulu, Turku, FI;
Ullamari Pesonen, Turku, FI;
Mika Scheinin, Naantali, FI;
Jukka T. Salonen, Jännevirta, FI;
Tomi-Pekka Tuomainen, Kuopio, FI;
Timo A. Lakka, Kuopio, FI;
Kristiina Nyyssönen, Kuopio, FI;
Riitta Salonen, Jännevirta, FI;
Jussi Kauhanen, Kuopio, FI;
Veli-Pekka Valkonen, Kuopio, FI;
OY Juvantia Pharma Ltd., , FI;
Abstract
This invention relates to a DNA sequence comprising a nucleotide sequence encoding a variant &agr; -adrenoceptor protein and to the variant &agr; -adrenoceptor protein as well as a method for screening a subject to determine if the subject is a carrier of a variant gene that encodes the variant &agr; -adrenoceptor protein. Further this invention relates to a method for treating a mammal suffering from vascular contraction of coronary arteries, the method comprising the step of administering a selective &agr; -adrenoceptor antagonist to the mammal and to transgenic animals comprising a human DNA molecule encoding human &agr; -adrenoceptor protein or the variant &agr; -adrenoceptor protein.