The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2004
Filed:
Feb. 25, 2000
Applicant:
Inventors:
James G. Barsoum, Lexington, MA (US);
Xiao-Qiang Qin, Winchester, MA (US);
Assignee:
Biogen, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 4/800 ; C12N 1/500 ; C12N 1/563 ; C12N 1/587 ; C02H 2/104 ;
U.S. Cl.
CPC ...
A61K 4/800 ; C12N 1/500 ; C12N 1/563 ; C12N 1/587 ; C02H 2/104 ;
Abstract
Methods and pharmaceutical compositions for modifying cells of a mammalian recipient with DNA encoding a secreted protein such as human interferon in situ are provided. The methods include forming a secreted protein expression system in vivo or ex vivo and administering the expression system to the mammalian recipient. The expression system and methods are useful for the localized and systemic delivery of interferons in situ.