The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2004
Filed:
Oct. 09, 2001
Applicant:
Inventors:
John W. Shiver, Doylestown, PA (US);
Daniel C. Freed, Limerick, PA (US);
Mary Ellen Davies, Norristown, PA (US);
Margaret A. Liu, Rosemont, PA (US);
Helen C. Perry, Lansdale, PA (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/06 ; C12N 5/00 ; C12Q 1/70 ; C12Q 1/68 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 5/06 ; C12N 5/00 ; C12Q 1/70 ; C12Q 1/68 ; C07H 2/104 ;
Abstract
Synthetic DNA molecules encoding HIV gag and modifications of HIV gag are provided. The codons of the synthetic molecules are codons preferred by the projected host cell. The synthetic molecules may be used as a polynucleotide vaccine which provides effective immunoprophylaxis against HIV infection through stimulation of neutralizing antibody and cell-mediated immunity.