The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2004
Filed:
Dec. 01, 1999
Applicant:
Inventors:
Thomas J. Chambers, St. Louis, MO (US);
Thomas P. Monath, Harvard, MA (US);
Farshad Guirakhoo, Melrose, MA (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 7/01 ; C12N 7/04 ; C12N 1/579 ; C12P 3/900 ; A61K 3/912 ;
U.S. Cl.
CPC ...
C12N 7/01 ; C12N 7/04 ; C12N 1/579 ; C12P 3/900 ; A61K 3/912 ;
Abstract
A chimeric live, infectious, attenuated virus containing a yellow fever virus, in which the nucleotide sequence for a prM-E protein is either deleted, truncated, or mutated, so that functional prM-E protein is not expressed, and integrated into the genome of the yellow fever virus, a nucleotide sequence encoding a prM-E protein of a second, different flavivirus, so that the prM-E protein of the second flavivirus is expressed.