The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 24, 2004
Filed:
Jan. 04, 2001
Applicant:
Inventors:
James Thompson, Ladera Ranch, CA (US);
Weidong Huang, Torrance, CA (US);
Assignee:
The Regent of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 ; G01N 3/3567 ; G01N 3/3574 ; G01N 3/3573 ; G01N 3/353 ;
U.S. Cl.
CPC ...
C12Q 1/00 ; G01N 3/3567 ; G01N 3/3574 ; G01N 3/3573 ; G01N 3/353 ;
Abstract
The present invention provides methods of determining whether test cells in a sample are cancerous or not and determining if lymphocytes are activated or not. The method measures the test cell's DNA ploidy and the cellular activity of an enzyme such as an esterase, which has altered expression in cancer cells. Esterase activity can be measured using fluorescent compounds such as fluorescein diacetate.