The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 2004
Filed:
Mar. 13, 2001
Applicant:
Inventors:
Raja R. Mamidi, Pomona, CA (US);
Leticia R. Regis, Lakewood, CA (US);
Mauro C. Mojica, Chino Hills, CA (US);
Hirokazu Ito, Arcadia, CA (US);
Takashi Goto, Arcadia, CA (US);
Assignee:
Alpha Therapeutic Corporation, Los Angeles, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/514 ; A61K 3/800 ; A61K 3/848 ; C07K 1/600 ;
U.S. Cl.
CPC ...
A61K 3/514 ; A61K 3/800 ; A61K 3/848 ; C07K 1/600 ;
Abstract
A method is provided for removing citrate, aluminum, and other multivalent ions and contaminants from proteins by adjusting the pH of a solution containing the protein to a pH from about 7 to about 10, and diafiltering the pH-adjusted solution against aqueous solutions which have a low level of ions.