The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2004
Filed:
May. 10, 2001
Andrew N. Tyler, Reading, MA (US);
NeoGenesis Drug Discovery, Inc., Cambridge, MA (US);
Abstract
A method and apparatus are provided for identifying unknown chemical structures that are related to one or more known structures. Measured masses of the unknown structures (US members) are compared with the expected masses of the known structures (DS members). The mass differences between US members and DS members are compared with changes in mass (&Dgr;M) between molecules analyzed as a function dependent upon structure (&Dgr;S). The mass difference is considered as a differential function, &Dgr;M/&Dgr;S, the result of which is calculated for each ion in the US when compared with each ion in the DS. These values are then correlated with values that would be expected based on assumed possible structural modifications. In addition, higher order differential functions, such as &Dgr; M/&Dgr;S , can be used as needed to allow for correlation of structures in which more than one structural motif has changed.