The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2004
Filed:
Oct. 23, 2002
Applicant:
Inventors:
Peter C. Ulrich, Portland, OR (US);
Anthony Cerami, Croton-on-Hudson, NY (US);
Assignee:
Kenneth S. Warren Institute, Ossining, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K 3/1425 ;
U.S. Cl.
CPC ...
C07D / ; A61K 3/1425 ;
Abstract
The present invention is directed to substituted naphthothiazolium, aromatic guanylhydrazones, and other compounds and compositions with anti-malarial activity useful for the treatment and prophylaxis of malaria. The compounds are provided for the treatment of malaria or the sequelae of malarial infection, for depolymerizing malaria pigment (hemozoin), and for ameliorating the adverse effects of hemozoin on host cells.