The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2004
Filed:
Jun. 06, 2001
Applicant:
Inventors:
Claudine S. Ashvar, Toluca Lake, CA (US);
Su-Ming Chiang, Canoga Park, CA (US);
David L. Emerson, Longmont, CO (US);
Ning Hu, San Gabriel, CA (US);
Gerard M. Jensen, Brea, CA (US);
Assignee:
OSI Pharmaceuticals, Inc., Melville, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 ;
U.S. Cl.
CPC ...
A61K 9/127 ;
Abstract
Liposomal encapsulated benzoquinazoline thymidylate synthase inhibitor formulations are provided. The liposomes have improved pharmacokinetics and enhanced efficacy as anti-tumor agents compared to the free drug. The formulations include liposomes comprising at least one phosphatidylcholine, a cholesterol, and a benzoquinazoline thymidylate synthase inhibitor.