The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2004
Filed:
Aug. 01, 2000
Applicant:
Inventors:
David A. Schwartz, Encinitas, CA (US);
Richard I. Hogrefe, San Diego, CA (US);
Assignee:
Solulink Bioscience, Inc., San Diego, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 1/904 ; C07H 1/920 ;
U.S. Cl.
CPC ...
C07H 1/904 ; C07H 1/920 ;
Abstract
Hydrazino, oxyamino and carbonyl-based monomers and methods for incorporation into oligonucleotides during enzymatic synthesis are provided. Modified oligonucleotides are provided that incorporate the monomers provided herein. Immobilized oligonucleotides and oligonucleotide conjugates that contain covalent hydrazone or oxime linkages are provided. Methods for preparation of surface bound oligonucleotides are provided. Methods for the preparation of oligonucleotide conjugates are also provided.