The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2004
Filed:
Jul. 15, 1999
Tatsuki Shiota, Kanagawa, JP;
Shinsuke Yamagami, Tokyo, JP;
Kenichiro Kataoka, Tokyo, JP;
Noriaki Endo, Tokyo, JP;
Hiroko Tanaka, Tokyo, JP;
Doug Barnum, San Francisco, CA (US);
Jonathan Greene, Palo Alto, CA (US);
Wilna Moree, San Diego, CA (US);
Michele Ramirez Weinhouse, Escondido, CA (US);
Christine M. Tarby, Cardiff, CA (US);
Other;
Abstract
Cyclic diamines of formula (I) or their pharmacologically acceptable acid addition salts, and their medical applications are described. These compounds inhibit the action of chemokines such as MIP-1a and/or MCP-1 on target cells, and are useful as a therapeutic drug and/or preventative drug in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissue.