The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2004

Filed:

May. 25, 2000
Applicant:
Inventors:

Janelle R. Anderson, Cambridge, MA (US);

Daniel T. Chiu, Seattle, WA (US);

Noo-Li Jeon, Cambridge, MA (US);

Sui Huang, Boston, MA (US);

Ravi Kane, Cambridge, MA (US);

Insung S. Choi, Cambridge, MA (US);

Donald E. Ingber, Boston, MA (US);

George M. Whitesides, Newton, MA (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/100 ; C12N 1/102 ; C12M 1/00 ; C07K 1/700 ; C07K 1/702 ;
U.S. Cl.
CPC ...
C12N 1/100 ; C12N 1/102 ; C12M 1/00 ; C07K 1/700 ; C07K 1/702 ;
Abstract

Microfluidic systems and methods are provided for fabricating complex patterns of materials, such as proteins, inorganic materials or cells, on surfaces. Complex, discontinuous patterns on surfaces can be formed incorporating or depositing multiple materials. A stamp structure has a flow path containing a series of interconnected channels. The channels include a first channel within an interior of the stamp structure, a second channel within a stamping surface of the structure defining a pattern, and a channel fluidically interconnecting the first and second channels. After contacting the stamp with a surface, a fluid is introduced into the flow path so that the fluid contacts the surface to form a pattern. In another embodiment, the stamp structure has two non-fluidically interconnected first and second flow paths defining first and second patterns of channels to produce non-continuous first and second patterns on a surface.


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