The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2004
Filed:
Jan. 02, 2003
Stefan Stutz, Basel, CH;
Peter Herold, Basel, CH;
Felix Spindler, Starrkirch-Wil, CH;
Walter Weissensteiner, Mödling, AT;
Thomas Sturm, Vienna, AT;
Speedel Pharma AG, Basel, CH;
Abstract
Compounds of formula (I), wherein R and R are, independently of one another, H, C -C alkyl, C -C halogenalkyl, C -C alkoxy, C -C alkoxy-C -C alkyl, or C -C alkoxy-C l-C alkyloxy, and R is C -C alkyl, are obtainable in high yields by stereoselective addition of R -substituted propionic acid esters to R - and R -substituted benzaldehydes of formula R—CHO to form corresponding 3-R-3-hydroxy-2-R -propionic acid esters, conversion of the OH group to a leavaing group, subsequent regioselective elimination to form 3-R-2-R -propenic acid esters, and their hydrolysis to form corresponding propenic carboxylic acids and their enantioselective hydrogenation, wherein R is (a).