The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 20, 2004
Filed:
Apr. 22, 2002
Anthony P. F. Turner, North Crawley, GB;
David C. Cullen, Cambridge, GB;
Sergiy A. Piletsky, Cranfield, GB;
Olena V. Piletska, Cranfield, GB;
Uwe Schedler, Berlin, DE;
David Weston, late of Aston Clinton, GB;
Cranfield University, Cranfield, GB;
Abstract
Reaction of a dialdehyde, particularly phthaldialdehyde (I), with R—Z where Z is a nucleophilic group (preferably SH) and R is polymerisable (e.g. allyl) gives a reactive thioacetal (V) which can react with an amine ligand L—NH to produce an isoindole (IV) which may be fluorescent. At some stage, generally before interaction with L—NH , the R groups are polymerised, possibly leading to self-assembly of the polymer on a metal or SH-bearing surface. Such a coated surface is useful as a transducer in assays or as a binding medium e.g. for chromatography.