The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6680169 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 20, 2004

Filed:

Apr. 16, 2001
Applicant:
Inventors:

Casey D. Morrow, Birmingham, AL (US);

Cheryl Jackson, Hoover, AL (US);

Jean Peduzzi, Clanton, AL (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/00 ; A61K 4/800 ;
U.S. Cl.
CPC ...
C12Q 1/00 ; A61K 4/800 ;
Abstract

The invention pertains to methods of delivering a polypeptide to a cell comprising (a) contacting a cell with a replicon having a non-poliovirus nucleic acid substituted for a nucleic acid which encodes at least a portion of a protein necessary for encapsidation, the non-poliovirus nucleic acid encoding, in an expressible form, a polypeptide or fragment thereof; and (b) maintaining the cells under conditions appropriate for introduction of the replicons into the cells. The cell may be within a subject and the polypeptide may be a therapeutic agent. The methods of the invention may be used to treat diseases including central nervous system disorders, infectious diseases, and cancer.


Find Patent Forward Citations

Morrow, Casey. (2004). Poliovirus replicons encoding therapeutic agents and uses thereof (U.S. Patent No. 6680169). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6680169

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