The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2004
Filed:
Sep. 19, 2001
Waldemar Priebe, Houston, TX (US);
Izabella Fokt, The Woodlands, TX (US);
Teresa Przewloka, Acton, MA (US);
Marta Krawczyk, Greenfield, WI (US);
Piotr Skibicki, Warsaw, PL;
Grzegorz Grynkiewicz, Lominaki, PL;
Roman Perez-Soler, New York, NY (US);
Houston Pharmaceuticals, Inc., Houston, TX (US);
Abstract
The present invention discloses new and novel substituted anthracyclines with modified alkyl-aromatic ring substitutions on the C-3′ of the sugar moiety or modified or unmodified alkyl-aromatic ring substitutions at the C-4′ of the sugar moiety. It also discloses novel methods for the preparation of sugar substrates and methods for the preparation of anthracycline antibiotics. These anthracycline analogs show high cytotoxicity in vitro against several tumor cell lines.