The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2003
Filed:
Jan. 29, 2002
Edgardo Laborde, Foster City, CA (US);
Louise Robinson, San Carlos, CA (US);
Fanying Meng, San Francisco, CA (US);
Brian T. Peterson, San Francisco, CA (US);
Hugo O. Villar, La Jolla, CA (US);
Steven E. Anuskiewicz, San Bruno, CA (US);
Yoshiro Ishiwata, Aichi-gun, JP;
Shoji Yokochi, Inabe-gun, JP;
Yukiharu Matsumoto, Gifu, JP;
Takuji Kakigami, Inabe-gun, JP;
Hideaki Inagaki, Anjoh, JP;
Takahito Jomori, Nagoya, JP;
Kouji Matsushima, Matsudo, JP;
Other;
Abstract
The present invention relates to chemical compounds, pharmaceutical compositions comprising said compounds, uses of said compounds and compositions, methods of treatment employing said compounds and compositions, and processes for preparing said compounds. Specifically, this invention relates to novel compounds which are antagonists of MCP-1 function and are useful in the prevention or treatment of chronic or acute inflammatory or autoimmune diseases, especially those associated with aberrant lymphocyte or monocyte accumulation such as arthritis, asthma, atherosclerosis, diabetic nephropathy, inflammatory bowel disease, Crohn's disease, multiple sclerosis, nephritis, pancreatitis, pulmonary fibrosis, psoriasis, restenosis, and transplant rejection. More specifically, the invention is related to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases.