The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2003
Filed:
Mar. 06, 2001
Robert Joseph Isfort, Fairfield, OH (US);
Russell James Sheldon, Fairfield, OH (US);
The Procter & Gamble Company, Cincinnati, OH (US);
Abstract
Screening methods for identifying compounds that bind to or activate corticotropin releasing factor receptors (CRF R) and regulate or potentially regulate skeletal muscle mass or function in vivo. Also disclosed are screening methods for identifying compounds that prolong or augment the activation of CRF Rs or of CRF R signal transduction pathways, increase CRF R or increase CRF expression are provided. Pharmaceutical compositions comprising CRF R agonists, antibodies to CRF R and methods for increasing skeletal muscle mass or function or for the treatment of skeletal muscle atrophy using CRF R as the target for intervention and methods for treatment of muscular dystrophies are described.