The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2003

Filed:

Sep. 19, 2001
Applicant:
Inventors:

Damir Janigro, Cleveland Heights, OH (US);

Mark S. McAllister, Rocky River, OH (US);

Assignee:

The Cleveland Clinic Foundation, Cleveland, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/34 ; C12M 3/06 ;
U.S. Cl.
CPC ...
C12M 1/34 ; C12M 3/06 ;
Abstract

A cell and tissue culture modeling device comprising a housing having an interior chamber, an inlet port in fluid communication with the internal chamber, an outlet port in fluid communication with the internal chamber, a plurality of hollow fibers disposed within the interior chamber and traversing the length of the housing between the inlet port and the outlet port. Each of the plurality of hollow fibers has an interior defining an intracapillary space and the interior chamber defines an extracapillary space unoccupied by the plurality of hollow fibers. To access the extracapillary space of the device, a portion of the housing is removable. The device can be used to conduct permeability, drug efficacy, and gene expression studies.


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