The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2003

Filed:

May. 18, 2000
Applicant:
Inventors:

Michael South, St. Louis, MO (US);

John J. Parlow, Arnold, MO (US);

Darin E. Jones, Ballwin, MO (US);

Brenda Case, St. Louis, MO (US);

Tom Dice, St. Charles, MO (US);

Richard Lindmark, Kirkwood, MO (US);

Michael J. Hayes, St. Louis, MO (US);

Melvin L. Rueppel, St. Louis, MO (US);

Horng-Chih Huang, Chesterfield, MO (US);

Wei Huang, Wildwood, MO (US);

Scott A. Long, Ballwin, MO (US);

Matthew Mahoney, St. Peters, MO (US);

William L. Neumann, St. Louis, MO (US);

David Reitz, Chesterfield, MO (US);

John I. Trujillo, Creve Coeur, MO (US);

Ching-Cheng Wang, Wildwood, MO (US);

Rhonda Wood, Maryland Heights, MO (US);

Qingping Zeng, Ballwin, MO (US);

Rick Fenton, Collinsville, IL (US);

Gary W. Franklin, Godfrey, IL (US);

Carrie Kusturin, Edwardsville, IL (US);

Assignee:

Pharmacia Corporation, Chicago, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; A61K 3/1495 ; A61P 7/02 ;
U.S. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; A61K 3/1495 ; A61P 7/02 ;
Abstract

The invention relates to substituted polycyclic aryl and heteroaryl pyrazinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.


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