The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 2003
Filed:
Feb. 01, 2001
Applicant:
Inventors:
Marc Abitbol, Paris, FR;
Yves Uteza, Villejuif, FR;
Maurice Menasche, Villiers-Le-Bel, FR;
Carine Bossard, Toulouse, FR;
Loic Van Den Berghe, Paris, FR;
Sebastian Bonnel, Paris, FR;
Hervé Prats, Toulouse, FR;
Jiri Honiger, Vitlejuif, FR;
Martin Neuner-Jehle, Gif-Sur-Yvette, FR;
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 ; A61K 3/800 ; A01N 6/300 ; C12N 5/00 ; C12N 5/06 ;
U.S. Cl.
CPC ...
A61K 9/14 ; A61K 3/800 ; A01N 6/300 ; C12N 5/00 ; C12N 5/06 ;
Abstract
Compositions and methods for reducing ocular diseases by implanting in an eye of a subject a composition comprising encapsulated cells which produce polypeptides, more particularly polypeptides that exhibit neurotrophic and/or anti-angiogenic activity. The encapsulation prevents the entry of host immune cells in the microcapsule while permitting the release of the polypeptide outside of the microcapsule.