The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 2003
Filed:
Apr. 28, 2000
Applicant:
Inventors:
David C. Greenspan, Gainesville, FL (US);
Sean Lee, Gainesville, FL (US);
Marlo tan Walpole, Gainesville, FL (US);
Assignee:
USBIOMATERIALS Corp., Alachua, FL (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 ; A61K 9/70 ; A61F 1/300 ; D02G 3/00 ; C12P 2/102 ;
U.S. Cl.
CPC ...
A61K 9/14 ; A61K 9/70 ; A61F 1/300 ; D02G 3/00 ; C12P 2/102 ;
Abstract
Compositions and methods for systemically minimizing the inflammatory effects of TNF-&agr; are disclosed. The compositions include particles of bioactive glass with a particle size less than about 20 &mgr;m, alone or in combination with anti-inflammatory agents and other therapeutic agents. The compositions can include an appropriate carrier for oral, intramuscular, intraperitoneal or intravenous administration. When administered to a patient, the particles bring about elevated levels of IL-6 and do not cause elevated levels of TNF-&agr;.