The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2003
Filed:
Mar. 25, 1998
Samuel J. Danishefsky, Englewood, NJ (US);
Dalibor Sames, New York, NY (US);
Samuel Hintermann, Basel, CH;
Xiao-Tao Chen, Newark, DE (US);
Jacob B. Schwartz, Ann Arbor, MI (US);
Peter Glunz, Wilmington, DE (US);
Govindaswami Ragupathi, New York, NY (US);
Philip O. Livingston, New York, NY (US);
Scott Kuduk, Harleysville, PA (US);
Lawrence Williams, New York, NY (US);
Sloan Kettering Institute for Cancer Research, New York, NY (US);
Abstract
The present invention provides novel &agr;-O-linked glycoconjugates such as &agr;-O-linked glycopeptides, as well convergent methods for synthesis thereof. The general preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the &agr;-O-linked glycoconjugates.