The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2003
Filed:
Dec. 22, 1999
Applicant:
Inventors:
Jutta Anna Türck, Cambridge, GB;
John Anthony Charles Archer, Cambridge, GB;
Assignee:
Advanced Technologies (Cambridge) Limited, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/04 ; C12N 1/563 ;
U.S. Cl.
CPC ...
C12N 5/04 ; C12N 1/563 ;
Abstract
A chemically inducible gene expression system is described. A chimeric gene having a first sequence comprising a promoter and a regulator polypeptide is linked with a second sequence comprising a promoter and a coding or non-coding sequence. Expression of the target gene of the second sequence is controlled by the regulator polypeptide which is acted upon by an inducer. The inducer is a chemical compound, such as OHP, which acts upon the OHP responsive regulator polypeptide, which can be obtained from Rhodococcus sp. V49. Various domain regions and complementary response elements are also described.